Videos

This page brings together my video work on hair loss, hormones, performance, and health optimization.

Everything here is either tested by me or deeply analyzed β€” with one goal: turning complex topics into clear, actionable insights.

Select a channel to explore

Philippe’s Blueprint

Philippe’s Blueprint is the structured, educational side of my work.

This is where I break down topics like hair loss, hormones, performance, and health optimization in a clear and systematic way.

The focus is on understanding:

  • how things work
  • why they work
  • and how to apply them responsibly

Content here is more research-driven and analytical, often going deeper into the underlying biology, pharmacology, and decision-making frameworks behind the strategies I cover.

Dutasteride vs finasteride: the three differences that decide which one you should take. 🎁 FREE PROTOCOL PDF + AUDIOBOOK: https://www.philippeb.pro/protocol Every compound, every dose, exactly what I run. Free. πŸ’Š RESEARCH COMPOUNDS (Anagen Inc), 10% off with code: blueprint β€’ RU58841 pre-mixed solution https://anageninc.com/ru58841-solution-50ml.html/?ref=26 β€’ K&B solution (the carrier designed for RU58841) https://anageninc.com/k-b-solution-50ml-designed-for-ru58841.html/?ref=26 β€’ JXL069 (suvomipic), the same molecule as PP405 https://anageninc.com/suvomipic-jxl069-solution/?ref=26 Always confirm a real third-party lab test before buying any research compound. πŸ“‹ MY CURRENT STACK β€’ Dutasteride 0.5mg daily, the systemic layer β€’ RU58841 and JXL069 topical, alternating nightly, the local layer β€’ Microneedling 1mm every 10 to 14 days, ketoconazole 2% shampoo 2 to 3x weekly πŸ’¬ Are you on finasteride, on dutasteride, or still deciding? Tell me which, and how long. Dutasteride blocks around 90% of the DHT in your blood, finasteride around 70%, and it grew more hair in the head to head trials. Settled, and still not a reason for every man to take it. I have been on dutasteride for over two years and it is the base of my protocol. The drug you should take is decided by three things the potency numbers never show: what the first three months of a switch look like, a formulation trap that only affects dutasteride, and how hard each drug is to get off. The regrowth gap is real and smaller than most people assume. Pooled across the comparative trials it is about 7 hairs per square centimetre at 24 weeks. Measurable, repeatable, and not a different head of hair. Keep the ten year number. In Yanagisawa's follow up of 532 men on finasteride, over 99% kept their hair or improved it after a decade. The drug that decides your hairline is not the strongest on paper, it is the one you can stay on for ten years. ⏱ CHAPTERS 0:00 Dutasteride blocks more DHT, and that is not the story 0:35 The three differences 0:54 The regrowth gap: 917 men, 24 weeks 1:28 The sexual side effect numbers 2:04 Difference 1: the switch shed 3:29 Difference 2: the formulation trap 4:16 The capsule that cut DHT by 13% 5:06 Difference 3: the exit, 8 hours vs 5 weeks 5:56 Insulin, body fat and estrogen 6:49 Ten years of finasteride, and the prostate data 7:55 The honest framing 8:23 Which one is yours 8:52 What I run now 9:40 The one number to keep βΈ» 🧴 INTELLIGENT, ketoconazole shampoo and microneedling, 10% off with code: PHILIPPE β€’ Shampoo and microneedling tools https://intelligent.shop/r?id=46ttrr β€’ Microneedling pen https://intelligent.shop/r?id=agfr62 βΈ» 🩸 DR PEN, 10% off with code: BLUEPRINT β€’ Dr Pen store, all devices and cartridges https://drpen.net/philippe β€’ Dr Pen A11 microneedling pen https://drpen.net/products/dr-pen-a11-microneedling-pen?sca_ref=11255954.cMPrNlf2HK βΈ» πŸ”΄ GROWBAND 2.0 (Hairguard), $100 off + free shipping, extra 10% with code: blueprint https://www.hairguard.com/?aff=philippeboissard βΈ» πŸ›’ THE REST OF MY ROUTINE (Amazon) β€’ Nizoral (ketoconazole shampoo) https://amzn.to/3SQeTVs β€’ Minoxidil https://amzn.to/3PmqFnt β€’ Blue vials and dropper https://amzn.to/3zFmgGq β€’ Powder wax https://amzn.to/43WfiKT βΈ» πŸ“š SOURCES β€’ Gubelin Harcha et al., JAAD: 917 men, 24 wks, dutasteride vs finasteride vs placebo. PMID 24411083 β€’ Zhou et al., pooled trials: +7.1 hairs/cm2 for dutasteride over finasteride at 24 wks β€’ Fossler et al., Clin Drug Investig: formulation changes dutasteride pharmacokinetics. β€’ Upreti et al., JCEM: dutasteride reduced insulin sensitivity and raised body fat, finasteride did not. PMID 24823464 β€’ Yanagisawa et al., 10 yrs, 532 men on finasteride 1mg: 91.5% improved, 99.1% maintained or improved β€’ Goodman et al., NEJM: long term follow up of the Prostate Cancer Prevention Trial. β€’ Half-lives: finasteride 6 to 8 hours, dutasteride terminal about 5 weeks (Propecia and Avodart labels) βΈ» πŸ”— Full protocols, research breakdowns and tools: https://www.philippeb.pro πŸ”” If this helped, subscribe. One deep dive every month, no fluff, just what is working. Disclosure: some links above are affiliate links and I earn a commission if you buy through them. ⚠️ Disclaimer: educational and research content only, not medical advice. RU58841, JXL069 and pyrilutamide are research chemicals and are NOT approved for human use. Finasteride, dutasteride and oral minoxidil are prescription medications. Speak to a qualified medical professional before starting or stopping any treatment. #Dutasteride #Finasteride #HairLoss #DHT #HairRegrowth #AndrogeneticAlopecia #MalePatternBaldness #HairLossTreatment #Avodart #HairScience ⚠️ Anagen Inc products (RU58841, JXL069 / suvomipic, pyrilutamide, K&B solution) are supplied for laboratory research use only. They are strictly not for human consumption and are not to be applied to the scalp or used on the body in any way.
Dutasteride vs Finasteride: The 3 Differences That Decide It
YouTube Video UExKSU0zUUhaUmswSTQ4SVgxQThyYVdQWjBZTEZwbnotSC4wNEU1MTI4NkZEMzVBN0JF
🎁 FREE: my full hair-loss protocol + the first chapters of my audiobook, no cost (doses, sourcing & research, written out): https://www.philippeb.pro/protocol He posted his progress on r/tressless and the before/after is real. But copy his stack exactly and you'll grow it back, then lose half of it. I break down what's the engine, what's the multiplier, what's just renting you thickness, and the one compound that finally moved his widow's peak, then the cleaner version of the same stack. πŸ“‹ HIS STACK (a little over 1 year) β€’ Dutasteride 0.5 mg, oral, daily (started on finasteride, switched partway) β€’ Topical minoxidil, scalp ~1.25 ml night + ~0.25 ml AM β€’ Topical minoxidil, beard ~0.75 ml nightly β€’ RU58841: 1.2 sprays night + 3 AM (~1 ml) β€’ Dermaroller 1.25 mm, every other week β€’ Diet ~150 g protein/day, plus creatine, multivitamin, ashwagandha βΈ» 🧴 INTELLIGENT, shampoo & microneedling, 10% off with code: PHILIPPE β€’ Ketoconazole shampoo & microneedling tools https://intelligent.shop/r?id=46ttrr β€’ Dermapen https://intelligent.shop/r?id=agfr62 βΈ» πŸ”΄ GROWBAND 2.0 (Hairguard), $100 off + free shipping, extra 10% with code: blueprint https://www.hairguard.com/?aff=philippeboissard βΈ» 🩸 DR PEN, 10% off with code: BLUEPRINT The 1 mm stamp I'd run weekly instead of his 1.25 mm roller: β€’ Dr Pen microneedling devices https://drpen.net β€’ Stayve Salmon DNA Gold Ampoule https://drpen.net/products/stayve-salmon-dna-gold-ampoule-10x8ml?sca_ref=10884181.w9hOKd46qi πŸ’¬ Which part of his stack would you cut first, the minoxidil or the roller? Drop it below, I read every comment. ⏱ CHAPTERS 0:00 The 1-year transformation (and the catch) 0:25 The full stack: how he got here 1:35 Dutasteride: the engine doing the work 2:35 Minoxidil: why half of it won't last 4:00 Microneedling: right idea, wrong depth 4:50 RU58841: the piece that moved his hairline 6:10 What I'd change about his stack 7:00 The real takeaway πŸ“š REFERENCED STUDIES β€’ Olsen et al. (2006). Dutasteride vs finasteride head-to-head hair count study. β€’ Dhurat et al. (2013). Microneedling vs minoxidil controlled trial. Journal of Cutaneous and Aesthetic Surgery. β€’ Randolph & Tosti (2021). Minoxidil for hair loss, a comprehensive review. Journal of the American Academy of Dermatology. πŸ”” If this helped, subscribe. I post one deep-dive like this every month. No fluff, just what's working. ⚠️ Disclaimer: This video is for educational and research purposes only. RU58841 is a research compound and is not FDA-approved for human use. Dutasteride and minoxidil are prescription/OTC medications that require a qualified medical professional to evaluate and monitor. Always consult a doctor before starting any treatment. #HairLoss #HairRegrowth #RU58841 #Dutasteride #Minoxidil #Microneedling #Tressless #RedditHairLoss #AndrogeneticAlopecia #HairScience #CrownRegrowth #ScalpHealth #AntiAndrogen #HairLoss2026
He Was Going Bald. 1 Year Later His Crown Was Full.
YouTube Video UExKSU0zUUhaUmswSTQ4SVgxQThyYVdQWjBZTEZwbnotSC42Qzk5MkEzQjVFQjYwRDA4
PP405 is already on sale as JXL069. The WHO just published the proof. 🎁 FREE PROTOCOL PDF + AUDIOBOOK: https://www.philippeb.pro/protocol Every compound, every dose, exactly what I run. Free. πŸ’Š RESEARCH COMPOUNDS (Anagen Inc), 10% off with code: blueprint β€’ JXL069 (suvomipic) https://anageninc.com/suvomipic-jxl069-solution/?ref=26 β€’ RU58841 pre-mixed solution https://anageninc.com/ru58841-solution-50ml.html/?ref=26 β€’ K&B solution (the carrier designed for RU58841) https://anageninc.com/k-b-solution-50ml-designed-for-ru58841.html/?ref=26 β€’ Pyrilutamide (KX-826) https://anageninc.com/pyrilutamide/?ref=26 Always confirm a real third-party lab test before buying any research compound. πŸ“‹ MY CURRENT STACK β€’ Dutasteride 0.5mg daily, the systemic layer β€’ RU58841 5% topical nightly, the local blocker β€’ JXL069 nightly, the compound in this video β€’ Microneedling 1mm every 10 to 14 days + ketoconazole 2% shampoo 2 to 3x per week πŸ’¬ Were you waiting on PP405? Comment where you are at, I read every one. A viewer called Toyn wrote into my question box and pointed out something I had missed. The World Health Organization published a new proposed generic drug name, suvomipic, and the CAS registry number attached to it is the same registry number that has been sitting on JXL069, the gray-market compound I have been putting on my own scalp for six months. Pelage has never published PP405's structure, which is why the argument about what it actually is has run for years. But a company applying for an INN has to disclose the molecule. That is what happened here. What this means: JXL069 and PP405 are the same molecule. What it does not mean: that they are the same drug. A topical is the molecule plus its vehicle, and Pelage's clinical formulation is not what is in a gray-market bottle. Different absorption, unverified purity, a dose you picked yourself, and no trial behind it. Correction: I have previously said on this channel and on my site that JXL069 and PP405 were separate compounds. That was wrong, and this video corrects it. ⏱ CHAPTERS 0:00 If you are waiting for PP405, stop waiting 0:15 Check it yourself in 10 seconds 0:34 What a CAS number actually is 1:30 The viewer who found it 2:04 Why it stayed hidden for years 2:35 The one place a company cannot hide the structure 3:13 The JXL series and the UCLA link 4:12 Same mechanism, same target 4:39 So why not just buy it? 5:01 The vehicle problem 5:37 What Anagen actually solved 6:40 My 12 week test 7:02 What I still cannot tell you 8:07 The correction: I was wrong 8:33 Watch this next βΈ» 🧴 INTELLIGENT, ketoconazole shampoo and microneedling, 10% off with code: PHILIPPE β€’ Shampoo and microneedling tools https://intelligent.shop/r?id=46ttrr β€’ Dermapen https://intelligent.shop/r?id=agfr62 βΈ» 🩸 DR PEN, 10% off with code: BLUEPRINT β€’ Dr Pen microneedling devices and cartridges https://drpen.net (code BLUEPRINT) β€’ Stayve Salmon DNA Gold Ampoule https://drpen.net/products/stayve-salmon-dna-gold-ampoule-10x8ml?sca_ref=10884181.w9hOKd46qi βΈ» πŸ”΄ GROWBAND 2.0 (Hairguard), $100 off + free shipping, extra 10% with code: blueprint https://www.hairguard.com/?aff=philippeboissard βΈ» πŸ›’ THE REST OF MY ROUTINE (Amazon) β€’ Nizoral (ketoconazole shampoo) https://amzn.to/3SQeTVs β€’ Minoxidil https://amzn.to/3PmqFnt β€’ Blue vials and dropper https://amzn.to/3zFmgGq β€’ Powder wax https://amzn.to/43WfiKT βΈ» πŸ“š SOURCES β€’ WHO Proposed INN List 135, published 20 July 2026 https://cdn.who.int/media/docs/default-source/international-nonproprietary-names-(inn)/pl135.pdf β€’ JXL069, CAS 2260696-63-5 β€’ Advances in the Development of Mitochondrial Pyruvate Carrier Inhibitors for Therapeutic Applications, Biomolecules 15(2):223 (the JXL series, Jung and coworkers, UCLA) βΈ» πŸ”— Full protocols, research breakdowns and tools: https://www.philippeb.pro πŸ”” If this helped, subscribe. One deep dive like this every month, no fluff, just what is working. Disclosure: I have an affiliate relationship with a vendor that sells this compound. Nothing here is a recommendation to buy or use a research chemical. ⚠️ Disclaimer: educational and research content only, not medical advice. RU58841, JXL069 and pyrilutamide are research chemicals and are NOT approved for human use. Finasteride, dutasteride and oral minoxidil are prescription medications. Speak to a qualified medical professional before starting or stopping any treatment. #PP405 #JXL069 #Suvomipic #HairLoss #HairRegrowth #Pelage #WHO #AndrogeneticAlopecia #HairScience #RU58841 ⚠️ Anagen Inc products (RU58841, JXL069 / suvomipic, pyrilutamide, K&B solution) are supplied for laboratory research use only. They are strictly not for human consumption and are not to be applied to the scalp or used on the body in any way.
PP405 Hair Loss Drug: It's Already On Sale As JXL069
YouTube Video UExKSU0zUUhaUmswSTQ4SVgxQThyYVdQWjBZTEZwbnotSC5CQkEwRDA0MDkwNUM2MDY1
This guy says finasteride broke him. Did it? Going through the claim honestly. 🎁 FREE PROTOCOL PDF + AUDIOBOOK: https://www.philippeb.pro/protocol Every compound, every dose, exactly what I run. Free. πŸ’Š RESEARCH COMPOUNDS (Anagen Inc), 10% off with code: blueprint β€’ RU58841 pre-mixed solution https://anageninc.com/ru58841-solution-50ml.html/?ref=26 β€’ Pyrilutamide (KX-826) https://anageninc.com/pyrilutamide/?ref=26 β€’ K&B solution (the carrier designed for RU58841) https://anageninc.com/k-b-solution-50ml-designed-for-ru58841.html/?ref=26 Always confirm a real third-party lab test before buying any research compound. πŸ“‹ HOW TO WEIGH A STORY LIKE THIS β€’ Persistent symptoms after stopping are reported in a minority and are genuinely contested β€’ Finasteride's plasma half life is about 6 hours, which makes some claimed timelines hard to explain pharmacologically β€’ The nocebo effect in this drug is measured and large, that is not the same as saying nobody is affected β€’ Both things can be true: the syndrome is real for some people, and the internet exaggerates the base rate β€’ Baseline bloodwork and an honest self assessment before you start is how you protect yourself πŸ’¬ Did you have side effects, and did they resolve? Honest answers both directions. A viral account of persistent side effects, taken seriously rather than dismissed or amplified. I go through what is documented in the literature, what the nocebo research shows, the half life problem with the timeline, and where the honest uncertainty is. βΈ» 🧴 INTELLIGENT, ketoconazole shampoo and microneedling, 10% off with code: PHILIPPE β€’ Shampoo and microneedling tools https://intelligent.shop/r?id=46ttrr β€’ Dermapen https://intelligent.shop/r?id=agfr62 βΈ» 🩸 DR PEN, 10% off with code: BLUEPRINT β€’ Dr Pen microneedling devices and cartridges https://drpen.net (code BLUEPRINT) β€’ Stayve Salmon DNA Gold Ampoule https://drpen.net/products/stayve-salmon-dna-gold-ampoule-10x8ml?sca_ref=10884181.w9hOKd46qi βΈ» πŸ”΄ GROWBAND 2.0 (Hairguard), $100 off + free shipping, extra 10% with code: blueprint https://www.hairguard.com/?aff=philippeboissard βΈ» πŸ›’ THE REST OF MY ROUTINE (Amazon) β€’ Nizoral (ketoconazole shampoo) https://amzn.to/3SQeTVs β€’ Minoxidil https://amzn.to/3PmqFnt β€’ Blue vials and dropper https://amzn.to/3zFmgGq β€’ Powder wax https://amzn.to/43WfiKT βΈ» πŸ“š REFERENCED STUDIES β€’ Mondaini et al. (2007): finasteride and sexual side effects, how many are nocebo? Journal of Sexual Medicine, 4(6), 1708-1712 β€’ Irwig & Kolukula (2011): persistent sexual side effects of finasteride. Journal of Sexual Medicine, 8(6), 1747-1753 β€’ Irwig (2012): depressive symptoms and suicidal thoughts among former finasteride users. Journal of Clinical Psychiatry, 73(9), 1220-1223 β€’ Cilio et al. (2025): post-finasteride syndrome, a true clinical entity? International Journal of Impotence Research β€’ Propecia (finasteride) US prescribing information, Merck: plasma elimination half life approximately 6 hours βΈ» πŸ”— Full protocols, research breakdowns and tools: https://www.philippeb.pro πŸ”” If this helped, subscribe. One deep dive like this every month, no fluff, just what is working. ⚠️ Disclaimer: educational and research content only, not medical advice. RU58841, JXL069 and pyrilutamide are research chemicals and are NOT approved for human use. Finasteride, dutasteride and oral minoxidil are prescription medications. Speak to a qualified medical professional before starting or stopping any treatment. #Finasteride #PostFinasterideSyndrome #SideEffects #HairLoss #MensHealth #HairRegrowth #DHT #HairScience #AndrogeneticAlopecia #PFS ⚠️ Anagen Inc products (RU58841, JXL069 / suvomipic, pyrilutamide, K&B solution) are supplied for laboratory research use only. They are strictly not for human consumption and are not to be applied to the scalp or used on the body in any way.
This Guy Says Finasteride Broke Him. Did It?
YouTube Video UExKSU0zUUhaUmswSTQ4SVgxQThyYVdQWjBZTEZwbnotSC4zMEQ1MEIyRTFGNzhDQzFB
Finasteride side effects: what is real, what is not, and the FDA's 32 case file. 🎁 FREE PROTOCOL PDF + AUDIOBOOK: https://www.philippeb.pro/protocol Every compound, every dose, exactly what I run. Free. πŸ’Š RESEARCH COMPOUNDS (Anagen Inc), 10% off with code: blueprint β€’ RU58841 pre-mixed solution https://anageninc.com/ru58841-solution-50ml.html/?ref=26 β€’ Pyrilutamide (KX-826) https://anageninc.com/pyrilutamide/?ref=26 β€’ K&B solution (the carrier designed for RU58841) https://anageninc.com/k-b-solution-50ml-designed-for-ru58841.html/?ref=26 Always confirm a real third-party lab test before buying any research compound. πŸ“‹ THE PRACTICAL TAKEAWAYS β€’ Compounded products are the weak link, one recalled batch tested at 147mg of undeclared minoxidil per capsule β€’ Topical finasteride still shows measurable systemic absorption, it is lower exposure, not zero β€’ Persistent symptoms are documented in a minority and are genuinely contested in the literature β€’ Buy from a real pharmacy, not a telehealth funnel with no pharmacist attached β€’ Baseline bloodwork before you start, so you can tell what changed πŸ’¬ What is your read on the risk, and did anything change for you? Comment it. The FDA issued an alert on compounded topical finasteride, and the worst story in that file did not involve finasteride at all. Here is what the 32 cases actually contained, what the telehealth lawsuit alleges, and how I weigh the risk on my own stack. ⏱ CHAPTERS 0:00 The FDA's warning, and the worst story did not involve finasteride 0:30 The pill that was not finasteride, 147mg of minoxidil per capsule 2:10 The FDA's 32 case file, what they actually found 3:35 The telehealth lawsuit and the case the WSJ documented 4:50 My actual stack and how I weigh the risk βΈ» 🧴 INTELLIGENT, ketoconazole shampoo and microneedling, 10% off with code: PHILIPPE β€’ Shampoo and microneedling tools https://intelligent.shop/r?id=46ttrr β€’ Dermapen https://intelligent.shop/r?id=agfr62 βΈ» 🩸 DR PEN, 10% off with code: BLUEPRINT β€’ Dr Pen microneedling devices and cartridges https://drpen.net (code BLUEPRINT) β€’ Stayve Salmon DNA Gold Ampoule https://drpen.net/products/stayve-salmon-dna-gold-ampoule-10x8ml?sca_ref=10884181.w9hOKd46qi βΈ» πŸ”΄ GROWBAND 2.0 (Hairguard), $100 off + free shipping, extra 10% with code: blueprint https://www.hairguard.com/?aff=philippeboissard βΈ» πŸ›’ THE REST OF MY ROUTINE (Amazon) β€’ Nizoral (ketoconazole shampoo) https://amzn.to/3SQeTVs β€’ Minoxidil https://amzn.to/3PmqFnt β€’ Blue vials and dropper https://amzn.to/3zFmgGq β€’ Powder wax https://amzn.to/43WfiKT βΈ» πŸ“š REFERENCED SOURCES β€’ FDA (2025): alert on adverse events from compounded topical finasteride, 32 cases reported to FAERS β€’ FDA (2020): MasterPharm voluntary recall of Finasteride Plus 1.25mg, capsules tested at 147mg of undeclared minoxidil β€’ Caserini et al. (2014): topical finasteride pharmacokinetics, measurable systemic absorption. International Journal of Clinical Pharmacology and Therapeutics β€’ Irwig (2012): persistent sexual side effects of finasteride in men with male pattern hair loss. Journal of Sexual Medicine β€’ Wall Street Journal: They Wanted a Quick Fix for Hair Loss. Instead, These Young Men Got Sick (Rolfe Winkler) βΈ» πŸ”— Full protocols, research breakdowns and tools: https://www.philippeb.pro πŸ”” If this helped, subscribe. One deep dive like this every month, no fluff, just what is working. ⚠️ Disclaimer: educational and research content only, not medical advice. RU58841, JXL069 and pyrilutamide are research chemicals and are NOT approved for human use. Finasteride, dutasteride and oral minoxidil are prescription medications. Speak to a qualified medical professional before starting or stopping any treatment. #Finasteride #SideEffects #FDA #TopicalFinasteride #HairLoss #HairRegrowth #MensHealth #DHT #AndrogeneticAlopecia #HairScience ⚠️ Anagen Inc products (RU58841, JXL069 / suvomipic, pyrilutamide, K&B solution) are supplied for laboratory research use only. They are strictly not for human consumption and are not to be applied to the scalp or used on the body in any way.
Finasteride Side Effects: What's Real and What Isn't
YouTube Video UExKSU0zUUhaUmswSTQ4SVgxQThyYVdQWjBZTEZwbnotSC41RTNBREYwMkI5QzU3RkY2
6 months on JXL069 (suvomipic), the same molecule as PP405: what it did. 🎁 FREE PROTOCOL PDF + AUDIOBOOK: https://www.philippeb.pro/protocol Every compound, every dose, exactly what I run. Free. πŸ’Š RESEARCH COMPOUNDS (Anagen Inc), 10% off with code: blueprint β€’ JXL069 (suvomipic) https://anageninc.com/suvomipic-jxl069-solution/?ref=26 β€’ RU58841 pre-mixed solution https://anageninc.com/ru58841-solution-50ml.html/?ref=26 β€’ K&B solution (the carrier designed for RU58841) https://anageninc.com/k-b-solution-50ml-designed-for-ru58841.html/?ref=26 β€’ Pyrilutamide (KX-826) https://anageninc.com/pyrilutamide/?ref=26 Always confirm a real third-party lab test before buying any research compound. πŸ“‹ MY CURRENT STACK β€’ Dutasteride 0.5mg daily, over a year β€’ RU58841 5% topical nightly, 6 years β€’ JXL069 nightly, the most recent addition, 6 months β€’ Microneedling every 10 to 14 days + ketoconazole shampoo 2 to 3x per week πŸ”— FULL PROTOCOLS, RESEARCH BREAKDOWNS AND TOOLS πŸ‘‰ https://www.philippeb.pro ⏱ CHAPTERS 0:00 The crown that one compound built in 6 months 1:30 How JXL069 actually works (MPC1 explained) πŸ’¬ What's your sticking point right now, crown, hairline, or temples? Drop it in the comments and I'll reply. I've been documenting my hair loss recovery for years. 6 years on RU58841, over a year on dutasteride. JXL069 is the most recent addition, and this is the honest 6-month review with the photos and the attribution. βΈ» 🧴 INTELLIGENT, ketoconazole shampoo and microneedling, 10% off with code: PHILIPPE β€’ Shampoo and microneedling tools https://intelligent.shop/r?id=46ttrr β€’ Dermapen https://intelligent.shop/r?id=agfr62 βΈ» 🩸 DR PEN, 10% off with code: BLUEPRINT β€’ Dr Pen microneedling devices and cartridges https://drpen.net (code BLUEPRINT) β€’ Stayve Salmon DNA Gold Ampoule https://drpen.net/products/stayve-salmon-dna-gold-ampoule-10x8ml?sca_ref=10884181.w9hOKd46qi βΈ» πŸ”΄ GROWBAND 2.0 (Hairguard), $100 off + free shipping, extra 10% with code: blueprint https://www.hairguard.com/?aff=philippeboissard βΈ» πŸ›’ THE REST OF MY ROUTINE (Amazon) β€’ Nizoral (ketoconazole shampoo) https://amzn.to/3SQeTVs β€’ Minoxidil https://amzn.to/3PmqFnt β€’ Blue vials and dropper https://amzn.to/3zFmgGq β€’ Powder wax https://amzn.to/43WfiKT βΈ» πŸ“š REFERENCED SCIENCE β€’ PP405 mechanism, MPC1 (mitochondrial pyruvate carrier 1) inhibition wakes dormant hair follicles by shifting the cell's energy state out of the low-power dormant mode. First genuinely new hair-loss mechanism in a decade. PP405 human trials are still in progress as of June 2026. β€’ Dhurat et al. (2013): microneedling vs minoxidil controlled trial. Journal of Cutaneous and Aesthetic Surgery β€’ Olsen et al. (2006): dutasteride vs finasteride head to head hair count study β€’ Frindik & Boccon-Gibod (2006): long term safety and efficacy of dutasteride βΈ» πŸ”— Full protocols, research breakdowns and tools: https://www.philippeb.pro πŸ”” If this helped, subscribe. One deep dive like this every month, no fluff, just what is working. ⚠️ Disclaimer: educational and research content only, not medical advice. RU58841, JXL069 and pyrilutamide are research chemicals and are NOT approved for human use. Finasteride, dutasteride and oral minoxidil are prescription medications. Speak to a qualified medical professional before starting or stopping any treatment. #HairLoss #JXL069 #PP405 #HairRegrowth #HairScience #RU58841 #AntiAndrogen #Dutasteride #Microneedling #CrownRegrowth #AndrogeneticAlopecia #ScalpHealth #HairResearch #HairLoss2026 ⚠️ Anagen Inc products (RU58841, JXL069 / suvomipic, pyrilutamide, K&B solution) are supplied for laboratory research use only. They are strictly not for human consumption and are not to be applied to the scalp or used on the body in any way.
Is This Better Than PP405 Everyone's Talking About?
YouTube Video UExKSU0zUUhaUmswSTQ4SVgxQThyYVdQWjBZTEZwbnotSC41NTZEOThBNThFOUVGQkVB
Finasteride vs dutasteride: up to 2x more hair. The 70% vs 90% DHT difference. 🎁 FREE PROTOCOL PDF + AUDIOBOOK: https://www.philippeb.pro/protocol Every compound, every dose, exactly what I run. Free. πŸ’Š RESEARCH COMPOUNDS (Anagen Inc), 10% off with code: blueprint β€’ RU58841 pre-mixed solution https://anageninc.com/ru58841-solution-50ml.html/?ref=26 β€’ JXL069 (suvomipic) https://anageninc.com/suvomipic-jxl069-solution/?ref=26 β€’ K&B solution (the carrier designed for RU58841) https://anageninc.com/k-b-solution-50ml-designed-for-ru58841.html/?ref=26 Always confirm a real third-party lab test before buying any research compound. πŸ“‹ THE COMPARISON β€’ Finasteride blocks type 2 5-alpha reductase, dutasteride blocks type 1 and type 2 β€’ Roughly 70% vs 90% serum DHT suppression β€’ Head to head hair count studies favour dutasteride β€’ Dutasteride has a much longer half life, which cuts both ways β€’ Both are prescription medications, this is your doctor's call πŸ’¬ Which one are you on, and were you ever offered the other? Comment it. The head to head trials are not close, and most men are never offered the stronger option first. Here is what the meta analysis found, how the two drugs differ mechanically, and the honest trade on side effects. ⏱ CHAPTERS 0:00 The pill your doctor does not hand you first 0:42 How DHT actually gets blocked (70% vs 90%) 1:25 The head to head trials and the meta analysis βΈ» 🧴 INTELLIGENT, ketoconazole shampoo and microneedling, 10% off with code: PHILIPPE β€’ Shampoo and microneedling tools https://intelligent.shop/r?id=46ttrr β€’ Dermapen https://intelligent.shop/r?id=agfr62 βΈ» 🩸 DR PEN, 10% off with code: BLUEPRINT β€’ Dr Pen microneedling devices and cartridges https://drpen.net (code BLUEPRINT) β€’ Stayve Salmon DNA Gold Ampoule https://drpen.net/products/stayve-salmon-dna-gold-ampoule-10x8ml?sca_ref=10884181.w9hOKd46qi βΈ» πŸ”΄ GROWBAND 2.0 (Hairguard), $100 off + free shipping, extra 10% with code: blueprint https://www.hairguard.com/?aff=philippeboissard βΈ» πŸ›’ THE REST OF MY ROUTINE (Amazon) β€’ Nizoral (ketoconazole shampoo) https://amzn.to/3SQeTVs β€’ Minoxidil https://amzn.to/3PmqFnt β€’ Blue vials and dropper https://amzn.to/3zFmgGq β€’ Powder wax https://amzn.to/43WfiKT βΈ» πŸ“š REFERENCED STUDIES β€’ Olsen et al. (2006): dose ranging study of dutasteride and finasteride in male pattern hair loss. JAAD, 55(6), 1014-1023 β€’ Gupta et al. (2022): relative efficacy of minoxidil and 5-alpha reductase inhibitors in androgenetic alopecia, a network meta analysis. JAMA Dermatology β€’ Andriole et al. (2010): effect of dutasteride on the risk of prostate cancer (REDUCE). NEJM, 362, 1192-1202 β€’ Drake et al. (1999): the effects of finasteride on scalp skin and serum androgens. JAAD, 41(4), 550-554 β€’ Clark et al. (2004): marked suppression of DHT by dutasteride. JCEM, 89(5), 2179-2184 βΈ» πŸ”— Full protocols, research breakdowns and tools: https://www.philippeb.pro πŸ”” If this helped, subscribe. One deep dive like this every month, no fluff, just what is working. ⚠️ Disclaimer: educational and research content only, not medical advice. RU58841, JXL069 and pyrilutamide are research chemicals and are NOT approved for human use. Finasteride, dutasteride and oral minoxidil are prescription medications. Speak to a qualified medical professional before starting or stopping any treatment. #Dutasteride #Finasteride #HairLoss #DHT #HairRegrowth #AndrogeneticAlopecia #HairScience #MalePatternBaldness #FinasterideAlternative #HairLossTreatment ⚠️ Anagen Inc products (RU58841, JXL069 / suvomipic, pyrilutamide, K&B solution) are supplied for laboratory research use only. They are strictly not for human consumption and are not to be applied to the scalp or used on the body in any way.
Finasteride Results vs Dutasteride: Up to 2x More Hair
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PP405's first before and after photos: 31% regrowth, 0% placebo. Real or cherry picked? 🎁 FREE PROTOCOL PDF + AUDIOBOOK: https://www.philippeb.pro/protocol Every compound, every dose, exactly what I run. Free. PP405 is the topical that is supposed to wake dormant follicles back up, and after months of big claims with no pictures they finally put before and after photos on a screen at AAD 2026. I walk through all three of their claims, what holds up, the one claim the photos cannot prove, and the data they quietly left out. I still think the mechanism could be huge. The way it is being sold has problems. πŸ’Š RESEARCH COMPOUNDS (Anagen Inc), 10% off with code: blueprint β€’ JXL069 (suvomipic) https://anageninc.com/suvomipic-jxl069-solution/?ref=26 β€’ RU58841 pre-mixed solution https://anageninc.com/ru58841-solution-50ml.html/?ref=26 β€’ K&B solution (the carrier designed for RU58841) https://anageninc.com/k-b-solution-50ml-designed-for-ru58841.html/?ref=26 β€’ Pyrilutamide (KX-826) https://anageninc.com/pyrilutamide/?ref=26 Always confirm a real third-party lab test before buying any research compound. πŸ“‹ WHAT I RUN WHILE PP405 IS YEARS AWAY (not "proven", just my stack) β€’ Systemic DHT control: dutasteride β€’ Local blocker at the follicle: RU58841 topical nightly β€’ The research compound I am running: JXL069 β€’ Scalp: microneedling every 10 to 14 days + ketoconazole shampoo πŸ’¬ Are you waiting on PP405, or running a proven stack right now? Drop where you are at in the comments, I read every one. ⏱ CHAPTERS 1:27 Claim 1, more hair from active follicles 1:58 Claim 2, new growth from dormant follicles 3:45 Claim 3, vellus to terminal (the measurement problem) 5:32 What they did not show (31% vs 0% placebo) βΈ» 🧴 INTELLIGENT, ketoconazole shampoo and microneedling, 10% off with code: PHILIPPE β€’ Shampoo and microneedling tools https://intelligent.shop/r?id=46ttrr β€’ Dermapen https://intelligent.shop/r?id=agfr62 βΈ» 🩸 DR PEN, 10% off with code: BLUEPRINT β€’ Dr Pen microneedling devices and cartridges https://drpen.net (code BLUEPRINT) β€’ Stayve Salmon DNA Gold Ampoule https://drpen.net/products/stayve-salmon-dna-gold-ampoule-10x8ml?sca_ref=10884181.w9hOKd46qi βΈ» πŸ”΄ GROWBAND 2.0 (Hairguard), $100 off + free shipping, extra 10% with code: blueprint https://www.hairguard.com/?aff=philippeboissard βΈ» πŸ“š REFERENCED STUDIES β€’ Pelage Pharmaceuticals: PP405 Phase 2a (NCT06393452), AAD 2026 presentation, positive Phase 2a results (June 2025) β€’ Koyama et al. (2016): standardized scalp massage increases hair thickness. Eplasty β€’ English & Barazesh (2019): self assessments of standardized scalp massage. Dermatology and Therapy β€’ Rebora & Guarrera (2002): kenogen, the latent phase of the hair cycle β€’ Torkamani et al. (2014): arrector pili muscle and the follicular stem cell niche. British Journal of Dermatology β€’ Yazdabadi et al. (2012): arrector pili muscle in androgenetic alopecia β€’ Humanized mouse model (2023): vellus to terminal reconversion is possible (PMC10599155) βΈ» πŸ”— Full protocols, research breakdowns and tools: https://www.philippeb.pro πŸ”” If this helped, subscribe. One deep dive like this every month, no fluff, just what is working. ⚠️ Disclaimer: educational and research content only, not medical advice. RU58841, JXL069 and pyrilutamide are research chemicals and are NOT approved for human use. Finasteride, dutasteride and oral minoxidil are prescription medications. Speak to a qualified medical professional before starting or stopping any treatment. #PP405 #HairLoss #HairRegrowth #Pelage #BeforeAndAfter #JXL069 #AndrogeneticAlopecia #HairLossResearch #HairLossTreatment #HairLoss2026 ⚠️ Anagen Inc products (RU58841, JXL069 / suvomipic, pyrilutamide, K&B solution) are supplied for laboratory research use only. They are strictly not for human consumption and are not to be applied to the scalp or used on the body in any way.
PP405's First Before & After Photos, Honestly Reviewed
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GT20029: a hair loss drug you apply twice a week, and it still grew hair in phase 2. 🎁 FREE PROTOCOL PDF + AUDIOBOOK: https://www.philippeb.pro/protocol Every compound, every dose, exactly what I run. Free. πŸ’Š RESEARCH COMPOUNDS (Anagen Inc), 10% off with code: blueprint β€’ RU58841 pre-mixed solution https://anageninc.com/ru58841-solution-50ml.html/?ref=26 β€’ Pyrilutamide (KX-826) https://anageninc.com/pyrilutamide/?ref=26 β€’ JXL069 (suvomipic), the same molecule as PP405 https://anageninc.com/suvomipic-jxl069-solution/?ref=26 β€’ K&B solution (the carrier designed for RU58841) https://anageninc.com/k-b-solution-50ml-designed-for-ru58841.html/?ref=26 Always confirm a real third-party lab test before buying any research compound. πŸ“‹ WHAT IS COVERED β€’ Why most of the GT20029 coverage missed the point β€’ How a degrader is fundamentally different from a blocker β€’ What Kintor's phase 2 actually measured, and what it did not β€’ The dose locked in for phase 3, and why β€’ What the safety signal looked like against placebo β€’ Why twice weekly dosing is a bigger deal than the hair count πŸ’¬ If you have been running a daily topical stack for 12+ months, minoxidil, RU58841, JXL069, anything, drop in the comments what you have learned about staying consistent. I read every one. It does not block the androgen receptor like RU58841 or topical finasteride. It tags it for destruction. One application keeps working long after the drug clears the scalp, which is how Kintor got results on a twice weekly schedule. Here is what phase 2 actually showed, the dose they locked in for phase 3, the safety signal, and how this changes what a serious stack looks like if it clears. ⏱ CHAPTERS 0:00 What GT20029 is 2:00 How every existing topical works, and why they have to stay there 17:00 What this means for your stack right now βΈ» 🧴 INTELLIGENT, ketoconazole shampoo and microneedling, 10% off with code: PHILIPPE β€’ Shampoo and microneedling tools https://intelligent.shop/r?id=46ttrr β€’ Dermapen https://intelligent.shop/r?id=agfr62 βΈ» 🩸 DR PEN, 10% off with code: BLUEPRINT β€’ Dr Pen microneedling devices and cartridges https://drpen.net (code BLUEPRINT) β€’ Stayve Salmon DNA Gold Ampoule https://drpen.net/products/stayve-salmon-dna-gold-ampoule-10x8ml?sca_ref=10884181.w9hOKd46qi βΈ» πŸ”΄ GROWBAND 2.0 (Hairguard), $100 off + free shipping, extra 10% with code: blueprint https://www.hairguard.com/?aff=philippeboissard βΈ» πŸ›’ THE REST OF MY ROUTINE (Amazon) β€’ Nizoral (ketoconazole shampoo) https://amzn.to/3SQeTVs β€’ Minoxidil https://amzn.to/3PmqFnt β€’ Blue vials and dropper https://amzn.to/3zFmgGq β€’ Powder wax https://amzn.to/43WfiKT βΈ» πŸ“š REFERENCED STUDIES β€’ Kintor Pharmaceutical (2024): GT20029 phase 2 results in androgenetic alopecia (investor disclosure and scientific session presentation) β€’ Dhurat et al. (2013): microneedling vs minoxidil controlled trial. Journal of Cutaneous and Aesthetic Surgery β€’ Olsen et al. (2006): dutasteride vs finasteride head to head hair count study β€’ Bekes, Langley, Crews (2022): PROTAC targeted protein degraders, the past is prologue. Nature Reviews Drug Discovery, 21, 181-200 βΈ» πŸ”— Full protocols, research breakdowns and tools: https://www.philippeb.pro πŸ”” If this helped, subscribe. One deep dive like this every month, no fluff, just what is working. ⚠️ Disclaimer: educational and research content only, not medical advice. RU58841, JXL069 and pyrilutamide are research chemicals and are NOT approved for human use. Finasteride, dutasteride and oral minoxidil are prescription medications. Speak to a qualified medical professional before starting or stopping any treatment. #GT20029 #HairLossDrug #PROTAC #Kintor #AndrogenReceptor #HairLossResearch #MaleHairLoss #Finasteride #RU58841 #HairLossStack ⚠️ Anagen Inc products (RU58841, JXL069 / suvomipic, pyrilutamide, K&B solution) are supplied for laboratory research use only. They are strictly not for human consumption and are not to be applied to the scalp or used on the body in any way.
Twice a Week and It Grew Hair (Phase 2 Data)
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