Oral vs Topical Minoxidil for Hair Loss: Which One Wins?
Randomized trials show oral and topical minoxidil are comparable for hair density. Here is what the evidence actually says, and how to choose between them.
Philippe Boissard
Philippe Boissard, M.Sc., is a hair loss researcher and author. He breaks down the science of androgenetic alopecia and the treatments men actually weigh up, working from the primary literature rather than marketing claims. New here? Start with his guide to how hair loss actually works.
Microneedling for Hair Loss: What the Trials Actually Show
The Dhurat 2013 RCT found 82% of men using microneedling plus minoxidil reported over 50% improvement. Here is what the evidence actually shows and where the caveats live.
JXL069 for Hair Loss: What It Is, and What We Actually Know
JXL069 is a preclinical MPC inhibitor being sold as a research chemical for hair regrowth. Here is what the mechanism means, and why the hype is running ahead of the evidence.
Hair-Growth Supplements: What’s Proven and What’s Oversold
Biotin, vitamin D, iron, zinc, selenium, marine complex: a researcher ranks the evidence and names the ones that can actually backfire. No hype, just numbers.
Hair Cloning and Follicle Neogenesis: Where the Science Really Is in 2026
Hair cloning headlines keep circulating. Here is what reactivation vs. true neogenesis actually means, what PP405 showed in Phase 2a, and when a real cure might arrive.
Dutasteride vs Finasteride for Hair Loss: What the Evidence Shows
Dutasteride suppresses about 90 percent of DHT versus roughly 70 percent for finasteride. Here is what the head-to-head trials actually found, and the catch.
DHT and Male Pattern Baldness: The Mechanism, Explained Properly
DHT shrinks hair follicles in men who are genetically sensitive to it. Here is exactly how that happens, why the pattern forms where it does, and what actually stops it.
Clascoterone (Breezula) for Hair Loss: The First New Drug Class in 30 Years?
Clascoterone 5% (Breezula) blocks DHT at the scalp receptor without systemic exposure. Phase 3 results, honest numbers, and what they actually mean for men.
The Hair Loss Reset Protocol: When You Have Tried Everything
A reset is systematic reassessment, not abandonment. Five steps: re-verify diagnosis, audit protocol, evaluate timeline, identify escalation move, reckon with realistic expectations.
Hair Loss Diet: Keto, Mediterranean, Plant-Based Compared
Diet for hair loss is real but secondary. Mediterranean has the data. Keto has a transition shedding phase. Plant-based is neutral when nutrients are managed. Honest read on what diet can and cannot do.